The Research for Patient Benefit funding stream has just announced that it is dropping the requirement for a Registration of Intention (ROI) from the next funding round (competition 13).
Therefore those researchers planning on submitting to the September deadline (24 September2010) will no longer have to have an ROI in advance.
RfPB is therefore now a one-stage application process, with no outline stage.
Remember however that to have the best chance of being funded you really do need to get support from the RDS as early as possible.

13 May, 2010